Agouti Signaling Protein (ASIP) (Middle Region) Peptid
ASIP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511781
Kurzübersicht für Agouti Signaling Protein (ASIP) (Middle Region) Peptid (ABIN5511781)
Target
ASIP
(Agouti Signaling Protein (ASIP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- ASIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ASIP (Agouti Signaling Protein (ASIP))
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Hintergrund
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In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9
Protein Size: 132 -
Gen-ID
- 434
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NCBI Accession
- NM_001672, NP_001663
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UniProt
- P42127
Target
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